AA amyloidosis associated with hepatitis B

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Abstract

We report a 13-year-old Indian boy with nephrotic syndrome caused by renal AA amyloidosis. Workup of the AA amyloidosis revealed chronic hepatitis B. Laser microdissection of the Congo-red-positive glomeruli and vessels followed by liquid chromatography and tandem mass spectrometry confirmed the presence of serum amyloid A (SAA) protein and ruled out hereditary and familial amyloidosis. Furthermore, mass spectrometry also detected a variant of SAA protein (SAA W71R). © 2010 The Author.

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Saha, A., Theis, J. D., Vrana, J. A., Dubey, N. K., Batra, V. V., & Sethi, S. (2011). AA amyloidosis associated with hepatitis B. Nephrology Dialysis Transplantation, 26(7), 2407–2412. https://doi.org/10.1093/ndt/gfr224

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