Chemical Composition and Antioxidant Activities of Extracts of Combretum quadrangulare Kurz Leaves Grown in An Giang Province, Vietnam

Abstract

Combretum quadrangulare leaves are an important herbal in traditional Vietnamese medicine due to their ability to cure various diseases and improve health. This study provided the investigation results of different organic solvents that affected the chemical composition, the extraction of polyphenol and flavonoid content, the antioxidant activity of Combretum quadrangulare extract obtained through the maceration method. Several classes of constituents in the extract of Combretum quadrangulare leaves were detected including flavonoids, volatile oils, tannins, etc. The ethanol extract had the highest polyphenol content found at 18.45 0.12 mg GAE/g extract. The diethyl ether leaves extract observed the highest falonoid with a value of 21.19 0.05 mg QE/g in. The antioxidant activities were shown through the IC50 values of 1514.50 25.65 µg/ml (DPPH) and 685.15 8.58 µg/ml (ABTS), individually.