Histopathological study of solitary thyroid nodules

Abstract

Aim: To determine the clinic-Histopathological spectrum nodules in patients of solitary thyroid nodules. Methods: A total number of 100 patients with diagnosis of solitary thyroid nodules were included in this cross-sectional study. Before hemi-thyroidectomy complete thorough general physical examination of all patients was done and vital signs were taken. In all patients’ hemi-thyroidectomy was done and biopsy specimens were taken and sent to the central laboratory of the hospital for determining the frequency of malignancy. Results: Mean age of studied patients was 41.81±12.33 years. There were more females 78% as compared to male patients which were only 22%. On histopathological reporting, adenoma was diagnosed in 36% patients, colloid nodules in 33% patients, cyst in only 9% patients and thyroiditis in only 5% patients. While malignant lesions were diagnosed in only 17% cases, out of which 10% cases were of papillary carcinoma and follicular carcinoma in 7% cases. Conclusion: Malignant lesions are found in 17% cases of solitary thyroid nodules (STN). In benign lesions adenoma and colloid nodules are very common.