A new way to understand chemical carcinogenesis and cancer prevention

Abstract

The ∆ values in this article have been developed by the author to estimate the electrophilic reactivity and carcinogenic potency of molecules. If a certain value of ∆ is regarded as the peak of carcinogenicity, then the substances with ∆ values that fall short of this peak, or that go beyond this peak, have a decrease in carcinogenicity. Keeping this principle in mind should help in avoiding the medicinal use of substances that are suspected to be carcinogenic.