Class A Orphans in GtoPdb v.2025.4

  • Alexander S
  • Mpamhanga C
  • Neubig R
  • et al.
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Abstract

The class A orphan GPCRs have been organised into the subfamilies listed below, to better segregate them based on evidence (or lack of evidence) for endogenous ligand or surrogate ligand interactions, and potential for deorphanization.

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Alexander, S. P. H., Mpamhanga, C., Neubig, R., Pawson, A. J., Pin, J.-P., Sharman, J. L., … Vanderheyden, P. (2025). Class A Orphans in GtoPdb v.2025.4. IUPHAR/BPS Guide to Pharmacology CITE, 2025(4). https://doi.org/10.2218/gtopdb/f16/2025.4

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