Effects of Morning versus Evening Administration of Perindopril on the Circadian Control of Blood Pressure in Cameroonian Type 2 Diabetes Individuals: A Crossover Randomized Trial

  • Liliane Mfeukeu K
  • Helene Ornella Bongha O
  • Jean-Claude K
  • et al.
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Abstract

Background: Renin-angiotensin system antagonists are the mainstays of blood pressure (BP) lowering strategies in people with diabetes. Perindopril a long half-life Angiotensin Converting Enzyme (ACE) inhibitor offers the advantage of a single daily dose, usually empirically taken in the morning. We therefore aimed to assess the influence of time of administration on the effect of Perindopril on circadian BP in type 2 diabetes (T2D) individuals with previously untreated stage 1 hypertension.

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Liliane Mfeukeu, K., Helene Ornella Bongha, O., Jean-Claude, K., Aurel Tiakouang, T., Mireille Claudia Abeng, B., Andre Michel, B., … Eugene, S. (2019). Effects of Morning versus Evening Administration of Perindopril on the Circadian Control of Blood Pressure in Cameroonian Type 2 Diabetes Individuals: A Crossover Randomized Trial. International Archives of Cardiovascular Diseases, 3(1). https://doi.org/10.23937/iacvd-2017/1710014

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