Guillain-Barré Syndrome with Bilateral Tonic Pupils

Abstract

A 53-year-old patient with Guillain-Barre syndrome preceded by herpes simplex virus infection developed bilateral tonic pupils with light-near dissociation. Pharmacological tests for pupils suggested postganglionic involvement of the parasympathetic and sympathetic nerves. A demyelinating process of peripheral autonomic nerves was suspected to be the cause of the tonic pupils and autonomic dysfunction. © 1994, The Japanese Society of Internal Medicine. All rights reserved.