Smart Drug Delivery Strategies Based on Porous Nanostructure Materials

Abstract

Abstract The control of drug delivery can have a great effect on its efficacy. An optimum concen‐ tration range of drugs can play a significant role in the human body, and it can cause harm to humans when it exceeds the range of the drug concentration. Recently, a variety of drug deliveries and their targeted systems have been studied to minimize drug loss and maximize the amount of drug accumulated in the required area, thus increasing drug bioavailability. In addition, we should especially consider the prevention of its harmful side-effects in the human body. Innovative drug delivery systems based on biodegrada‐ ble, natural or synthetic polymers, micro- or nano-particles, lipoproteins, micelles, TiO2 nanotube arrays (TNTs), nanoporous anodic aluminum oxide (AAO), and so on were de‐ veloped, which combined magnetic targeting and stimulus-responsive in drug delivery systems. The composition of delivery carriers and the stimulus-responsive elements proved stimulus-responsive drug release as a smart drug delivery system.