A review of mathematical model describing insulin delivery system for type 1 diabetes

Abstract

Even though technologies on diabetes treatment keep expanding from time to time, blood glucose control problem is still being a crucial issue raised by scientists and researchers. Most of the Diabetes do not achieve an optimum blood glucose level despite of persistent treatment taken. Therefore, an efficient control is essential to enhance diabetes treatment. A comprehensive, accurate, reliable and simple mathematical model is being focused in developing a control algorithm on blood glucose level. It is hoped that the insulin delivery mechanism can be simplified and the life quality of patient can be improved. A good working mathematical model should be able to mimic the dynamic and complexity of insulin glucose interactions so as to provide valuable information on safety and effectiveness of the control system in patient’s body. In this paper, we review the mathematical model which describes insulin delivery mechanism for Type 1 Diabetes and present the results of the simulation work representing insulin-glucose interactions in the body.