Safety and Efficacy of Dexmedetomidine, Ketofol, and Propofol for Sedation of Mechanically Ventilated Patients

Abstract

INTERVENTION: Group1: 30 patients will receive ketofol an initial bolus dose (500mcg/kg) of ketamine/propofol1:1 ( Group2: 30 patients will receive loading dose infusion of dexmedetomidin (precedex ) diluted in 0. Group3: 30 patients will receive Propofol (diprivan) undiluted as an infusion of 1‐3mg/kg/h, after a CONDITION: ; Respiratory ; mechanically ventilated patients in the intensive care unit. mechanically ventilated patients in the intensive care unit. Respiratory PRIMARY OUTCOME: Ramsay Sedation Scale INCLUSION CRITERIA: ¿ Adult patients(18yr or older) ¿ The patients whose will require a minimum of 24h artificial ventilation after complex major surgery ¿ The patients need for sedation