Objective Evaluation of the Longevity of A Calcium Hydroxylapatite-Based Filler (Radiesse®)

Abstract

Background: Calcium hydroxylapatite (CaHA) based soft-tissue filler (Radiesse® , Merz) is categorised as a biodegradable collagen-stimulating implant. It is comprised of a suspension of 25-45 micron diameter microspheres of CaHA(30%) in a carboxymethylcellulose (CMC) gel carrier (70%) and is one of the most well researched soft-tissue fillers. However, great discrepancies exist in the literature regarding the duration of clinical effect with the implant, ranging from only 6 to 24 months.