Abstract
BACKGROUND: Ovarian tumors during pregnancy are rare. There is sparse clinical evidence about the safety of chemotherapy in this situation. CASE: A 34-year-old woman was diagnosed by ultrasonography at 15 1/2 weeks of pregnancy with a Krukenberg tumor. She was treated with surgical removal and 10 courses of the combination of 5-fluorouracil, folinic acid, and irinotecan every 2 weeks until the 36th week of her pregnancy. The neonate was born without complications, and at age 4 months, showed normal development and no teratogenic effects. CONCLUSION: In this case, irinotecan started at the second trimester and was safely used at full adjuvant dose. © 2009 The American College of Obstetricians and Gynecologists.
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CITATION STYLE
Taylor, J., Amanze, A., Di Federico, E., & Verschraegen, C. (2009). Irinotecan use during pregnancy. Obstetrics and Gynecology, 114(2 PART 2 SUPPL.), 451–452. https://doi.org/10.1097/AOG.0b013e3181a1d478
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