The origin of a double insertion of homogeneously staining regions in the house mouse (Musmusculus musculus)

Abstract

A high resolution analysis of the G-band patterns of normal and aberrant chromosomes 1, bearing two linked insertions of homogeneously staining regions (HSRs) in the house mouse (Mus musculus musculus) reveals the inverted pattern of the euchromatic region between the HSRs. On the basis of this analysis a hypothesis on the origin of the aberrant chromosome is put forward: The double insertion is a result of an inversion of the chromosome 1 of Mus musculus domesticus bearing a single insertion of HSR. The proximal breakpoint is localized inside the HSR, and the distal one between subbands E3 and E4. © 1990, The Genetical Society of Great Britain.