Synthesis of α,ω-bis(oxazolidinone)polyoxyethylene via a lithium bromide-catalyzed reaction of oligoethylene glycol diglycidyl ethers with isocyanates

Abstract

The synthesis of bis(oxazolidinone)polyoxyethylene derivatives 2a-h from oligoethylene glycols diglycidyl ethers 1a-e and isocyanates is reported. The reaction was achieved by lithium bromide and tributylphosphine oxide. These bis-oxazolidinones may have important antibacterial activity. Copyright © Taylor & Francis Group, LLC.