Green synthesis, cytotoxicity, antioxidant and photocatalytic activity of CeO2 nanoparticles mediated via orange peel extract (OPE)

Abstract

The advancement of metal oxide nanomaterials via green synthesis protocol proved leading tools for nanotechnology applications especially as drug deliver carriers, biosensors and clinical pharmaceutical. The aim of the current study was to synthesize cerium dioxide nanoparticles (CeO2 NPs) using orange peel extract (OPE) and evaluate its enactment for the antioxidant, anticancer and photocatalytic activities. Structural and morphological investigations of green synthesized CeO2 NPs was examined by using X-ray diffraction (XRD), transmission electron Microscopy (TEM), Fourier transform infrared (FTIR) spectra, Raman spectroscopy and ultraviolet-visible spectroscopy (UV-vis). Further, cytotoxicity and ROS activity of green synthesized CeO2 NPs exposed against cervical cancerous cells (HeLa). Green synthesized CeO2 NPs revealed the considerable antioxidant activity and hold effective methylene blue (MB) dye degradation in the presence of sunlight.