Profil Klinis Pasien Meningoensefalitis di Instalasi Rawat Intensif RSUP. Dr. Kariadi Semarang

Abstract

Introduction: Meningoencephalitis is an inflammation of the brain and brain membranes. The onset of the disease varies depending on the etiology. Meningoencephalitis causes fever, headaches, meningitis, changes in mental status, and/or seizures. Meningoencephalitis is diagnosed on an individual basis, with laboratory and imaging tests to back it up. Objective: The study's goal was to determine the clinical profile of adult meningoencephalitis patients admitted to Semarang's Dr. Kariadi Hospital's Intensive Care Unit. Method: The clinical profile includes clinical manifestations, laboratory examination results, and imaging. Results and discussion: There were 8 adult meningoencephalitis patients; women were more than men (63%); age groups that had the same high incidence (25%) were 17-25 years, 26-35 years, and 36-45 years; all patients presented with decreased consciousness (GCS ≤13); the most common clinical manifestations of meningoencephalitis are headache (100%), neck stiffness (87.5%), lateralization (75%), fever (62.5%); most of the patients (62%) had a lumbar puncture, with clear/colorless results (100%), high protein levels (80%), decreased glucose levels (60%), PMN cell pleocytosis (60%), MN cell pleocytosis ( 20%), there was no pleocytosis (20%); 75% of patients had a CT scan of the head, with half the imaging results supporting the picture of infection (50%). Conclusions: Meningoencephalitis patients mostly are women and young adults. Unconsciousness, headache were clinical manifestations that all patients experienced. The CSF examination results showed that bacteria became the first etiology. A Head CT scan did not always show an appearance of infection.