Immunophenotypic Characterization of Normal Bone Marrow Stem Cells

Abstract

The recent advances in flow cytometry technology and the emergence of new high-speed flow cytometers have given a valuable contribute to diminish this problem in two different (but complementary) aspects: 1) by reducing dramatically the acquisition time period, making it more reasonable to study minor cell populations; and 2) by increasing the number of parameters that can be analyzed per cell at the same time, which is critical to improve the immunophenotypic characterization of those not-well characterized cell populations that lack a specific known marker.