Chemical constituents from the aerial parts of Flourensia laurifolia

Abstract

Twenty-seven compounds were isolated and characterized from the aerial parts (leaves and stems) of the endemic Mexican plant Flourensia laurifolia: eight sesquiterpenes, seven flavones, three flavonols, two flavanes, two monoterpenes, one flavanonol, one benzofurane, one cinnamic acid, one triterpene, and one sterol. Twelve of these compounds are isolated for the first time within the Flourensia genus; the remaining fifteen had already been isolated from other plants of Flourensia. The compounds’ structures were established through a complete 1D and 2D-NMR spectroscopic analysis. F. laurifolia showed a chemical relationship with at least ten other Flourensia species sharing compounds and biosynthetic pathways that originate them; mainly with F. resinosa, F. cernua, and F. oolepis; and to a lesser degree with F. campestris, F. heterolepis, F. macrophylla, F. riparia, F. ilicifolia, F. retinophylla, and F. thurifera. The flavones-flavonols and eudesmanes could be considered the chemophenetic markers of F. laurifolia. The monoterpene 1 and the sesquiterpene 3 are new isolated natural products, and their spectroscopic and spectrometric data are reported here for the first time.