Methane sulphonic acid is green catalyst in organic synthesis

Abstract

Methane sulphonic acid is an alkanesulphonic acid and its chemical formula is CH 3 SO 3 H. MSA is a strong acid having pKa= 1.9 and completely ionized in 0.1M in an aqueous solution and has small affinity to oxidize organic compounds, less corrosive and toxic than other mineral acids. MSA is also biodegradable and not evolve toxic gases. Therefore MSA is considered as green acid. Therefore its use in organic synthesis attracts many chemists to use in organic synthesis. In this review we described the MSA catalyzed organic transformation.