Study of the effect of altitude on the measurement of glycated haemoglobin using point-of-care instruments

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Abstract

We measured the glycated haemoglobin (HbA 1c) levels of a total of 24 non-diabetic volunteers and diabetic patients using a point-of-care (POC) analyser in three Cameroonian cities at different altitudes. Although 12 to 25% of duplicates had more than 0.5% (8 mmol/mol) difference across the sites, HbA 1c values correlated significantly (r = 0.89-0.96). Further calibration studies against gold-standard measures are warranted.

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Veigne, S. W., Sobngwi, E., Nouthe, B. E., Sobngwi-Tambekou, J., Balti, E. V., Limen, S., … Mbanya, J. C. (2015). Study of the effect of altitude on the measurement of glycated haemoglobin using point-of-care instruments. Cardiovascular Journal of Africa, 26(1), 38–40. https://doi.org/10.5830/CVJA-2014-078

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