Thrombolytic activity of curcuma amada and curcuma caesia

Abstract

Objective: To compare the thrombolytic activity of Curcuma amada and Curcuma caesia. Methods: Hydroalcoholic extractions of C. amada and C. caesia were prepared. Clot lysis potential of the extracts was checked, and the results were statistically analyzed. Results and Conclusion: On comparing the thrombolytic potential, the percentage of clot lysis of synthesized silver nanoparticle using C. caesia (51%) was found to be higher than C. amada (34.7%) extract. Similarly, C. caesia extract (38.75±2.217) showed higher percentage of clot lysis than C. amada (34.74±6.074). The mean percentage of clot lysis of rhizome extracts and synthesized silver nanoparticle was statistically more significant (p<0.05) when compared to the positive control streptokinase and negative control water. Active component involvement analysis will be helpful to utilize the C. amada and C. caesia as potent therapeutic agent.