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TREM2 enables amyloid β clearance by microglia

Cell Research
DOI: 10.1038/cr.2015.37
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Abstract

In a recent paper published in Cell, Wang et al. report that deficiency of triggering receptor expressed on myeloid cells 2 (TREM2) augments amyloid β accumulation and neuronal loss in a mouse model of Alzheimer's disease. TREM2 acts as a signaling receptor involved in innate immunity for the natural clearance of this toxic protein by microglia.

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APA

Rivest, S. (2015, May 7). TREM2 enables amyloid β clearance by microglia. Cell Research. Nature Publishing Group. https://doi.org/10.1038/cr.2015.37

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