Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging

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Abstract

Multiplexed antibody-based imaging enables the detailed characterization of molecular and cellular organization in tissues. Advances in the field now allow high-parameter data collection (>60 targets); however, considerable expertise and capital are needed to construct the antibody panels employed by these methods. Organ mapping antibody panels are community-validated resources that save time and money, increase reproducibility, accelerate discovery and support the construction of a Human Reference Atlas.

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Quardokus, E. M., Saunders, D. C., McDonough, E., Hickey, J. W., Werlein, C., Surrette, C., … Radtke, A. J. (2023). Organ Mapping Antibody Panels: a community resource for standardized multiplexed tissue imaging. Nature Methods, 20(8), 1174–1178. https://doi.org/10.1038/s41592-023-01846-7

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