Progress in the Use of Platelet-Rich Plasma to Treat Vitiligo and Melasma

Abstract

There have been numerous therapeutic innovations in the field of dermatology during the past decade. Of these, platelet-rich plasma (PRP) has recently aroused significant interest, particularly in treating acne scars and alopecia, and in skin rejuvenation. In contrast, less attention has been paid to the use of PRP as a treatment for other dermatologic conditions, such as vitiligo and melasma. The objective of this literature review was to focus on conditions of pigmented dermatosis and consolidate the available evidence regarding PRP usage for the practicing dermatologist. We reviewed the relevant literature on PRP treatment on vitiligo and melasma, and concluded that PRP has a significant improvement in pigmented dermatosis. Although numerous studies support the use of PRP, more research is needed to standardize the protocols for obtaining, processing, and applying PRP, as well as to determine the biological and molecular bases of its function.