Pathways of triple negative breast cancer

Abstract

Breast malignances is among the most predominant malignancies in females worldwide. Annually, more than 1.5 million women (25 percent of all female cancer patients) are diagnosed with breast cancer each year. Sex, age, gene mutations, family history and an unhealthy lifestyle are among the risk factors which can raise the chance of breast cancer. Women are 100 times more likely than men to get breast cancer. Breast cancer: The word breast cancer is an umbrella term for many breast cancer sub-types. These subtypes of breast cancer differ in their clinical presentation, reveal distinct patterns of gene expression, and have different genetic and molecular features. Breast cancer is a condition in which the breast tissues become malignant cells. This happens in both sexes, but is very rare in males [1]. Breast cancer encompasses a heterogeneous group of diseases. It is composed of numerous biological subtypes that have discrete behaviors and responses to therapy. Gene expression studies identified several distinct breast cancer subtypes. These studies divide breast cancers into subtypes that diverge significantly in prognosis as well as in the therapeutic targets existing in the cancer cells [2] .