Synthesis of 4-acetyl (or carbethoxy) -5-methyl-1-heterocyclylpyrazoles

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Abstract

Reaction of heterocyclylhydrazines (1a-f) with 3-ethoxymethylenepentane-2,4-dione (2) and ethyl 2-ethoxymethylene-3-oxobutyrate (3) yields exclusively 4-acetyl-5-methyl-1-heterocyclylpyrazoles (4a-f) and 4-carbethoxy-5-methyl-1-heterocyclylpyrazoles (5a-f), respectively, in good yields.

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Singh, S. P., Kapoor, J. K., & Sadana, A. K. (2001). Synthesis of 4-acetyl (or carbethoxy) -5-methyl-1-heterocyclylpyrazoles. Heterocyclic Communications, 7(1), 49–54. https://doi.org/10.1515/HC.2001.7.1.49

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