Total Synthesis of Amentoflavone

Abstract

An efficient total synthesis of amentoflavone, a valuable natural product, utilizing Suzuki coupling with pinacolatoboronflavone derivatives and iodoflavone was reported for the first time in this work. The method can be applied to the synthesis of various other C-C biflavonoidsand biphenyls, therefore the current work could serve as an excellent solution to the availability of many bioactive natural biflavonoids.