A peristaltic micropump based on the fast electrochemical actuator: Design, fabrication, and preliminary testing

Abstract

Microfluidic devices providing an accurate delivery of fluids at required rates are of considerable interest, especially for the biomedical field. The progress is limited by the lack of mi-cropumps, which are compact, have high performance, and are compatible with standard micro-fabrication. This paper describes a micropump based on a new driving principle. The pump con-tains three membrane actuators operating peristaltically. The actuators are driven by nanobubbles of hydrogen and oxygen, which are generated in the chamber by a series of short voltage pulses of alternating polarity applied to the electrodes. This process guaranties the response time of the actuators to be much shorter than that of any other electrochemical device. The main part of the pump has a size of about 3 mm, which is an order of magnitude smaller in comparison with con-ventional micropumps. The pump is fabricated in glass and silicon wafers using standard clean-room processes. The channels are formed in SU-8 photoresist and the membrane is made of SiNx. The channels are sealed by two processes of bonding between SU-8 and SiNx. Functionality of the channels and membranes is demonstrated. A defect of electrodes related to the lift-off fabrication procedure did not allow a demonstration of the pumping process although a flow rate of 1.5 µl/min and dosage accuracy of 0.25 nl are expected. The working characteristics of the pump make it at-tractive for the use in portable drug delivery systems, but the fabrication technology must be improved.