Optical nonlinearity in measurement of urea and uric acid in blood

Abstract

The Z-scan technique is a simple and effective tool for determining nonlinear optical properties of materials. This technique is utilized in meas-urement of urea and uric acid in blood. The nonlinear refractive index of urea and uric acid are found to vary linearly with concentration. Hence by calculating the nonlinear refractive index it is possible to measure their concentra-tion in the sample. The results of this method are found to be in good agreement with the conventional colorimetric method.