A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters

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Abstract

Alternative promoters are frequently used to regulate tissue- and cancer-specific transcription, and variation in promoter usage is associated with cancer patient survival.

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Demircioğlu, D., Cukuroglu, E., Kindermans, M., Nandi, T., Calabrese, C., Fonseca, N. A., … Göke, J. (2019). A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters. Cell, 178(6), 1465-1477.e17. https://doi.org/10.1016/j.cell.2019.08.018

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