Bioelectrical signal analysis of mouse cardiomyocyte culture recorded on thin-film-transistor sensor arrays

Abstract

The dynamical property of the heart bioelectrical system is closely associated with cardiac diseases. For this reason there is a growing interest in the development of system analysis for studying the cardiac signaling network. In this article, the electrical potentials of cardiac muscle cells have been measured on an array of microelectrodes using Thin-Film-Transistor (TFT) technology, and electrophysiological data were analyzed. This study shows the possibility of accurately analyzing extracellular signals measured on TFT arrays.