Verrucous-Squamous Carcinomas of the Oral Cavity: A Clinicopathologic Study of 104 Cases

Abstract

One hundred four patients had verrucous carcinomas of the oral cavity. Our study documents, for the first time, the coexistence of foci of less-differentiated squamous carcinoma within verrucous lesions of the oral cavity (20%). We confirm previous observations that verrucous lesions tend to recur in the form of less-differentiated carcinomas. Finally, we demonstrate that surgery is indeed the treatment of choice for verrucous carcinomas of the oral cavity, although irradiation can be used to treat selected patients. © 1984 American Medical Association. All rights reserved.