Click Chemistry Complexes as A platform For Biological Application: A review

Abstract

The 1,2, 3-triazole moiety is the main biomolecule formed from the chemistry of clicks. Click chemistry is cycloaddition reaction including Copper or ruthenium catalyzed with azide-alkyne and resulting in five membered rings. Click chemistry and its complexes are utilized as anti-cancer, anti-microbial, anti-tuberculosis, anti-viral, anti-diabetic, anti-malarial, ant?-leishmanial and neuroprotective agents and also in fluorescent technology. Biological targets required a method containing the linker feature like 1,2, 3-triazoles moiety and a new set of 1,2,3-triazole consisting hybrids and conjugates. The present review summarizes developments over the last few years in application complexes of 1,2, 3-triazole analogue. Scientists of organic fields, clinical chemistry, photochemistry, and pharmacology will benefit from this study. This review offers essential knowledge to the interested researchers.