Non-Mendelian Genetic Aspects in Spinocerebellar Ataxias (SCAS): The Case of Machado-Joseph Disease (MJD)

Abstract

Manuela Lima1,2, Jacome Bruges-Armas1,3 and Conceicao Bettencourt1,2,4 1Genetic and Arthritis Research Group, Institute for Molecular and Cell Biology (IBMC), University of Porto, Porto 2Center of Research in Natural Resources (CIRN) and Department of Biology, University of the Azores, Ponta Delgada 3Servico Especializado de Epidemiologia e Biologia Molecular, Hospital de Santo Espirito de Angra do Heroismo 4Laboratorio de Biologia Molecular, Instituto de Enfermedades Neurologicas, Fundacion Socio-Sanitaria de Castilla-La Mancha, Guadalajara 1,2,3Portugal 4Spain