General method for selective mono-boc protection of diamines and thereof

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Abstract

Here we report a simple and efficient protocol for selectively diamine protection with Boc using Me3SiCl or SOCl2 as HCl source in “one-pot” procedure. This methodology is extended to 1,2to 1,8-diamines to obtain the corresponding mono-Boc protected diamines.

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Servín, F. A., Romero, J. A., Aguirre, G., Grotjahn, D., Somanathan, R., & Chávez, D. (2017). General method for selective mono-boc protection of diamines and thereof. Journal of the Mexican Chemical Society, 61(1), 23–27. https://doi.org/10.29356/jmcs.v61i1.124

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