The hydroboration of enamines

Abstract

This review describes the hydroboration of enamines in chronological order covering early work to give β-amino alcohols and reduction products and then our more recent work to give β-aminoorganoboranes and their subsequent conversion into β-amino alcohols, β-aminoboronic esters and acids, and olefins. Analytical methods to determine the enantiomeric excess (ee) of the β-amino alcohols obtained from the asymmetric hydroboration of enamines are also described. ©ARKAT-USA, Inc.