Immunometabolic control of homeostasis and inflammation

Abstract

Chronic inflammation underlies an array of chronic, non-communicable diseases, including various cardiovascular and metabolic diseases and cancer. Recent studies have also shown that the mechanisms involved in regulating immunity and metabolism are intricately linked. The term immunometabolism refers to that linkage. In this review, we will discuss immune cell-mediated regulation of metabolic homeostasis and pathology in major metabolic tissues. A particular focus is on macrophages, which play diverse roles in the inflammatory processes induced in non- communicable diseases. Rec.6/30/2015,