Trichomonal vaginitis. A 24 hr regimen of nimorazole compared with a 7 day regimen of metronidazole

Abstract

A 24 hr regimen of nimorazole (1 g orally at 12 hrly intervals for three doses) was compared with metronidazole (200 mg three times daily for 7 days) in the treatment of trichomonal vaginitis. The two treatment schedules were given to alternate patients, pregnant women being excluded. One hundred cases were treated on each schedule; roughly one fifth of the patients in each group defaulted. There were no observed failures with either schedule. The reasons for these exceptionally good results are discussed.