Electrochemical determination of adrenaline at Ru(III) schiff base complex modified carbon electrodes

Abstract

The anodic oxidation of adrenaline on ruthenium(III) Schiff base complex modified carbon electrodes was used for determination of adrenaline by flow-injection analysis, cyclic voltammetry, differential pulse voltammetry and hydrodynamic amperometry. The electrocatalytic properties of ruthenium(III) complex at glassy and screen printed carbon electrodes were enhanced by addition of cellulose acetate and multi-walled carbon nanotubes. Flow injection amperometric measurements were performed at 100 mV vs. Ag / AgCl in 0.1 M phosphate buffer pH 7.5 at 0.4 mL min-1 flow rate. Novel sensor provided a linear dynamic range up to 50 mg L-1 of adrenaline with detection limit of 53 μg L-1 at physiological pH. Determination of adrenaline in commercial sample was carried out by flow-injection method with excellent recoveries 99.8-101 %.