COVID-19 Vaccine, Contraceptive, Viscosity and Safety Margin Change

Abstract

COVID-19 vaccine is the new vaccine aiming at containment of the COVID-19 outbreak. For vaccination, an interaction with personal medication is an important concern. Since the contraceptive pill is widely used and the interrelationship with the COVID-19 vaccine is possible. A study to assess interrelationship is interesting. Clinical mathematical model analysis is used to estimate viscosity change comparing COVID-19 vaccine recipients with and without contraceptive use. A safety margin value for no hyperviscosity is also calculated. A decreased safety margin for no hyperviscosity is expected in one who takes a contraceptive pill. It is necessary to monitor for blood viscosity change in vaccine recipients who use the contraceptive pill, and if it is possible, the contraceptive pill should be stopped before vaccination.