Recent Advances in the Biological Importance of Rhodanine Derivatives

Abstract

Heterocyclic compounds are an important part of the synthetic medicinal chemistry. They offer a high degree of structural variety and have proven to be widely useful as therapeutic agents. Heterocyclic compounds play an important role in the biological processes. They are widespread as natural products. Heterocyclic compounds are widely found in nature categorically in plant alkaloids, nucleic acids, anthocyanins, and fla‐ vones. They are also present as in chlorophyll and hemoglobin. Additionally, some pro‐ teins, hormones, and vitamins also contain aromatic heterocyclic system. Heterocycles have huge potential as the most promising molecules as lead structures for the design of new drugs. About one half of over 6 million compounds recorded so far in chemical ab‐ stracts are heterocyclic. The proposed book chapter entitled, Recent Advances in the Biologi‐ cal Importance of Rhodanine Derivatives gives an outline of importance and applications of the various rhodanine derivatives in medicinal chemistry from 2004 to 2014