Fixation artefact in an intra-operative frozen section: A potential cause of misinterpretation

Abstract

The intra-operative histological assessment of fresh tissue can provide valuable diagnostic information and guide surgical management, however, even a limited exposure to standard fixation agents can potentially compromise analysis. Defined handling strategies should exist to facilitate the receipt of all specimens, in their optimal state, by the laboratory. © 2007 Thomson and Wallace; licensee BioMed Central Ltd.