Endocarditis caused by rhodotorula successfully treated with 5 fluorocytosine

Abstract

A 7 yr old boy suffering from aortic regurgitation and mitral stenosis and regurgitation was admitted with endocarditis caused by Rhodotorula pilimanae, and was treated successfully with orally administered antifungal agent, namely 5 fluorocytosine (5 FC). A dose of 100 mg per kg body weight, divided into 4 equal parts, was prescribed. After a prolonged febrile period his temperature dropped to normal on the fourth day of 5 FC therapy. Review of the published reports disclosed few cases of endocarditis due to Rhodotorula species and this case seems to be the first treated with 5 FC. Followup in one yr, after discharge from the hospital, revealed no evidence of relapse.