Correlation of Pulmonary Tuberculosis in HIV Positive Patients and its Association with CD4 Count

Abstract

-INTRODUCTION-HIV/AIDS pandemic is responsible for the resurgence of Tuberculosis worldwide, resulting in increased morbidity and mortality. Co-infection with HIV infection leads to difficulty in both the diagnosis and treatment of Tuberculosis, increased risk of death, treatment failure and relapse. OBJECTIVE-The present study highlights the correlation of Pulmonary Tuberculosis in HIV positive cases and its association with CD 4 count. MATERIAL & METHODS-A total of 72 known case of HIV were screened for tuberculosis infection by clinical examination, radiology & ZN staining. RESULTS AND CONCLUSIONS-From our study 60 (83.33%) were diagnosed as tuberculosis and 12 (16.67%) were negative. More common HIV infection in case of male 48 (66.67%). Out of 60 tuberculosis infection 53 (88.33%) were diagnosed as Pulmonary Tuberculosis and 7 (11.67%) were diagnosed as Extrapulmonary Tuberculosis. The result of study emphasizes that co-infection of tuberculosis in HIV/AIDS patient is a concern. There is direct correlation between CD 4 counts depletion and Pulmonary Tuberculosis in HIV/AIDS patients.