The Fabrication Porous hydroxyapatite Scaffold Using Sweet Potato Starch as a Natural Space Holder

Abstract

A study has been conducted to evaluate the effect of sintering temperature on the mechanical and physical properties of hydroxyapatite ceramics. In this study the fabrication of porous hydroxyapatite derived from bovine bone obtained from food scraps of local restaurant. Bovine bone is cleaned and boiled to remove the fat content. Then cut into small pieces to facilitate the process of making powder. Further calcined with a temperature of 600°C, then crushed with mortar to produce powder. Sweet potato is used as a Space holder which act as pore makers in this HA ceramic. A ball milling process with a speed of 225 rpm rotation for 1 hour was used to mix raw material. The powder is sintered with temperature of 1050, 1100 and 1200 ° C then the powder is characterized by XRD to evaluate the formation of HA and ß-TCP phases. The results of this study obtained a hydroxyapatite sample with a maximum shrinkage 44.46% at a temperature of 1200°C and the highest porosity was 49.35% at 1050°C and the best compressive strength of 4.41 MPa achieved at 1200°C. Morphology of sample was observed using SEM and reveal porosity size of about 17.5μm and 12.5μm. Interconnected porous was clearly observed on the sintered samples. Porosity is expected to facilitate the circulation of body fluids and encourage the growth of cells.