Current and future treatment of metabolic syndrome and type 2 diabetes in children and adolescents

Abstract

In children, the first line of prevention and treatment of obesity, dyslipidemia, hypertension, and type 2 diabetes remains dietary modification, increased physical activity, and behavior modification. Certain medications used for treatment of dyslipidemia, hypertension, and type 2 diabetes in children have been well studied and approved for this use. However, more well-controlled studies are needed in children for medications approved for adults in the treatment of obesity. Bariatric surgery as a treatment option for severely obese adolescents remains investigational.