The description of corrected count increment on one hour and 24 hours after platelet apheresis transfusion in Sanglah General Hospital Denpasar

Abstract

Introduction: Evaluating the response after platelet transfusion is vital to measure the success rate of the therapy and plan the subsequent management of patients. The evaluation can be done by calculating the corrected count increment (CCI) at 1 hour and 24 hours after transfusion. The purpose of this study was to determine the therapeutic response to apheresis platelet transfusion by measuring the CCI at 1 hour and 24 hours after transfusion. Methods: This study was a cross-sectional descriptive study of patients who received apheresis platelet transfusions. In total, 35 samples were examined for platelet counts before and after transfusion. The CCI was measured at 1 hour and 24 hours after transfusion. Descriptive statistical analysis was performed to calculate the percentage and mean count. Result: The mean count of transfused platelets was 2.7 × 10¹¹ / unit. The mean platelet count before transfusion was 18.5 × 10³ / μL. The mean platelet increment at 1 hour was 25.4 10³ / μL and 24 hours was 22.6 × 10³ / μL. The mean CCI ± SD at 1 hour and 24 hours was 15,036.63 ± 13,709.73 and 13,625.60 ± 13,580 respectively. A total of 63% of samples reached the target CCI at the 1-hour measurement, while the remaining 37% did not. Meanwhile, 60% of the samples reached the CCI target at the 24-hour measurement, while 40% did not. Conclusion: The response to apheresis platelet transfusion by measuring the CCI reached the target in 63% of patients at 1 hour after transfusion and 60% of patients at 24 hours after transfusion.