Tamizaje Fitoquímico y Cálculo de Rendimiento de Sapogeninas Esteroidales de Tres Procedencias de Solanum Quitoense Var. Septentrionale "Naranjillo"

Abstract

This research includes the study of aerial parts (fruits) of lulo de monte (Solanum quitoense var. Septentrionale).The main objective of thisresearch was to determine the secondary metabolites and especially the presence and quantity of alkaloidal saponins, which are common in the Solanaceae family. These substances are used as precursors for the manufacture of several steroid-type drugs, hormones and anti-inflammatories. The study was conducted with species of three different origins and three different maturing stages gathered in the department of Cundinamarca, Colombia between 2.400 and 2.600 meters above sea level during the period from March to June. Sapogenins were extracted, isolated and purified through various techniques used for this purpose. The presence of saponins was proved through physical and chemical analysis, and the structural elucidation through nmr and ir spectroscopic techniques. The presence of hecogenin in green fruits from the three sources was determined. This molecular structure corresponds to a non-steroidal sapogenin reported in this species.