Abstract
On endothelial cells, the TGFb/BMP-9 coreceptor, endoglin, emerged as a promising antiangiogenic target in colorectal cancer. Its promiscuous expression by cancer-associated fibroblasts (CAF) emerges to facilitate metastasis. The multitarget impact of neutralizing endoglin may offer added benefit in controlling colorectal cancer.
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CITATION STYLE
APA
Becker, L. M., & LeBleu, V. S. (2018). Endoglin targeting in colorectal tumor microenvironment. Clinical Cancer Research, 24(24), 6110–6111. https://doi.org/10.1158/1078-0432.CCR-18-2023
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