Real-time effects of COVID-19 pandemic lockdown on pediatric respiratory patients

Abstract

Objective: A national lockdown was implemented in Israel to slow the viral spread of COVID-19. We assessed the real-time effects of the lockdown on disease expression and lifestyle modifications in pediatric patients with chronic respiratory disorders. Methods: An anonymous electronic questionnaire was distributed during lockdown (March–May 2020) to caregivers of patients with chronic respiratory disorders. The primary outcome was change in disease expression and the secondary outcomes were changes in lifestyle and caregivers’ emotional status. Results: The clinical status of one-third of the 445 participating patients (age 0–18 years) reportedly improved, including decreased respiratory symptoms (n = 133, 33%), exacerbation frequency (n = 147, 35%), and use of reliever medications (n = 101, 27.4%). The condition of ~10% of the patients worsened. Clinical improvement was noted mostly in young patients <5 years (p =.001), asthmatic patients (p =.033), and patients with multiple underlying respiratory disorders (p =.015). Patients whose condition significantly worsened were more likely to be >5 years (p